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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN20A
All Species:
15.76
Human Site:
S177
Identified Species:
49.52
UniProt:
Q4JDL3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4JDL3
NP_001035816.1
420
48423
S177
N
L
P
G
E
F
N
S
G
N
Q
P
S
N
R
Chimpanzee
Pan troglodytes
XP_001136909
653
73228
S410
N
L
P
G
E
F
N
S
G
N
Q
P
S
N
R
Rhesus Macaque
Macaca mulatta
XP_001109336
420
48468
S177
N
L
P
G
E
F
K
S
G
N
Q
P
N
N
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55082
426
49100
S183
T
L
P
D
D
F
N
S
G
N
T
L
Q
N
R
Rat
Rattus norvegicus
A1L1L3
421
48562
S178
I
P
P
D
D
F
K
S
G
Y
E
L
Q
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515862
889
97591
V636
K
P
L
D
Q
C
L
V
G
Q
T
K
E
N
R
Chicken
Gallus gallus
XP_001234615
841
94302
T596
K
P
V
D
D
C
R
T
A
K
A
P
E
N
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185050
396
44869
D159
A
K
K
A
Q
N
K
D
K
N
R
F
R
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64
93.5
N.A.
N.A.
64.3
66
N.A.
23.8
25.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
64.3
96.6
N.A.
N.A.
77
79.3
N.A.
33.5
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
60
40
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
N.A.
N.A.
66.6
53.3
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
0
0
0
0
13
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
38
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
38
0
0
0
0
0
13
0
25
0
0
% E
% Phe:
0
0
0
0
0
63
0
0
0
0
0
13
0
0
0
% F
% Gly:
0
0
0
38
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
13
13
0
0
0
38
0
13
13
0
13
0
0
0
% K
% Leu:
0
50
13
0
0
0
13
0
0
0
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
38
0
0
0
0
13
38
0
0
63
0
0
13
100
0
% N
% Pro:
0
38
63
0
0
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
0
0
0
0
25
0
0
0
0
13
38
0
25
0
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
0
13
0
13
0
88
% R
% Ser:
0
0
0
0
0
0
0
63
0
0
0
0
25
0
0
% S
% Thr:
13
0
0
0
0
0
0
13
0
0
25
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
13
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _